Villarroel's work explores the transformative potential of biomimicry in speculative design, focusing on the chemical processes of nature to envision novel materials and systems. Her research delves into the intricate mechanisms of biological systems, from the molecular level to macroscopic structures, seeking to translate these principles into speculative designs that challenge conventional thinking. Through rigorous analytical methods and a high tolerance for risk, Villarroel pushes the boundaries of material science and design, speculating on future applications with unforeseen properties. Her practice is driven by a deep curiosity about the elegant solutions found in nature and a desire to explore the unexplored territories of bio-inspired design. Rooted in the stark landscapes and unique biodiversity of rural Chile, her work subtly reflects the resilience of life in these environments, engaging with indigenous knowledge systems related to the properties of native flora and fauna to further enrich her speculative explorations.